Elevated Aβ aggregates in feces from Alzheimer’s disease patients: a proof-of-concept study
Thus, fecal Aβ aggregates constitute a non-invasive biomarker candidate for diagnosing AD. Whether digestion-resistant Aβ aggregates in feces are secreted via the liver and bile or directly from the enteric neuronal system remains to be elucidated.
Authors
- Gereon R. Fink (ORCID: https://orcid.org/0000-0002-8230-1856)
- Markus Tusche (ORCID: https://orcid.org/0000-0003-0530-7469)
- Alexandra Dybala
- Gültekin Tamgüney (ORCID: https://orcid.org/0000-0002-6933-5154)
- Hannes Gramespacher (ORCID: https://orcid.org/0000-0002-9980-4978)
- Tuyen Bujnicki (ORCID: https://orcid.org/0000-0002-7191-8455)
- Victoria Kraemer‐Schulien (ORCID: https://orcid.org/0000-0002-7413-7646)
- Marlene Pils (ORCID: https://orcid.org/0000-0002-1506-3675)
- Anja Schaffrath
- Oliver Bannach (ORCID: https://orcid.org/0000-0002-7438-3791)
- Lara Blömeke (ORCID: https://orcid.org/0000-0002-8861-9224)
- Maximilian H.T. Schmieschek
- Fabian Rehn (ORCID: https://orcid.org/0000-0001-8815-0684)
- Oezguer A. Onur (ORCID: https://orcid.org/0000-0001-8336-7075)
- Janine Kutzsche (ORCID: https://orcid.org/0000-0003-0271-7390)
- Michael T. Barbe (ORCID: https://orcid.org/0000-0003-1149-8054)
- Pelin Özdüzenciler (ORCID: https://orcid.org/0000-0002-9235-2147)
- Dieter Willbold (ORCID: https://orcid.org/0000-0002-0065-7366)
Institutions
- Forschungszentrum Jülich (DE)
- University of Cologne (DE)
- University Hospital Cologne (DE)
- Heinrich Heine University Düsseldorf (DE)
- Hochschule Düsseldorf University of Applied Sciences (DE)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s13195-024-01597-3
- Citations
- 6
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.96
Funders
- Forschungszentrum Jülich
- Heinrich-Heine-Universität Düsseldorf