Ten hour donor heart ischemic time with 10ºC static storage
Utilization of 10ºC static storage safely extended both ischemic time and travel radius in heart transplantation. A 57-year-old man with ischemic cardiomyopathy, a left ventricular assist device (LVAD), and end-stage renal disease was listed for combined heart-kidney transplant. The donor hospital in Anchorage, AK, was located approximately 2,700 nautical miles and 8 hours from the recipient center. The organ was transported in 10ºC static storage with over 10 hours of ischemic time and had superb early allograft function. Excellent outcomes with extended ischemic times can be achieved without machine perfusion, provided good recovery, storage, and implant techniques are followed.
Authors
- Chris Schwartz
- Swaroop Bommareddi
- Brandon Petree (ORCID: https://orcid.org/0000-0002-5566-028X)
- John M. Trahanas (ORCID: https://orcid.org/0000-0001-8644-5489)
- Yatrik J. Patel (ORCID: https://orcid.org/0000-0001-8672-5755)
- Matthew D. Bacchetta (ORCID: https://orcid.org/0000-0003-4456-4484)
- William Tucker (ORCID: https://orcid.org/0009-0003-5601-1091)
- Steve Devries
- Brian Lima (ORCID: https://orcid.org/0000-0002-2555-2229)
- Ashish Shah (ORCID: https://orcid.org/0000-0002-3375-7865)
- Mark Petrovic
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- JHLT Open
- Published
- 2024-10-13
- DOI
- https://doi.org/10.1016/j.jhlto.2024.100163
- Citations
- 5
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- Cystic Fibrosis Foundation
- National Institutes of Health
- Congressionally Directed Medical Research Programs