MELATONIN ENHANCES TEMOZOLOMIDE-INDUCED APOPTOSIS IN GLIOBLASTOMA AND NEUROBLASTOMA CELLS
Our findings indicate that the combination of MEL with a low dose of TMZ may serve as an upstream inducer of apoptosis. This suggests the potential development of a novel selective therapeutic strategy as an alternative to TMZ for the treatment of both glioblastoma and neuroblastoma.
Authors
- Oğuzhan Doğanlar (ORCID: https://orcid.org/0000-0003-2654-7269)
- Ayten Bostancı
Institutions
- Trakya University (TR)
Publication Details
- Journal
- Experimental Oncology
- Published
- 2024-10-09
- DOI
- https://doi.org/10.15407/exp-oncology.2024.02.087
- Citations
- 7
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 1.92