GAP JUNCTION FUNCTION IS ESSENTIAL FOR SURVIVAL OF ACUTE LYMPHOBLASTIC LEUKEMIA CELLS

These studies demonstrate that acute lymphoblastic cell survival is impaired by interference with the gap junction function. The development of drugs targeting gap junctions may provide a novel approach to the therapy of acute lymphoblastic leukemia.

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Publication Details

Journal
Experimental Oncology
Published
2024-10-09
DOI
https://doi.org/10.15407/exp-oncology.2024.02.110
Primary Topic
Connexins and lens biology
Type
article
Field-Weighted Citation Impact
0.00
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article

GAP JUNCTION FUNCTION IS ESSENTIAL FOR SURVIVAL OF ACUTE LYMPHOBLASTIC LEUKEMIA CELLS

E.A. Edwards, Dominic Schenone, Urmila Sivagnanalingam, Craig A. Mullen et al.
Experimental Oncology
Connexins and lens biology
article

GAP JUNCTION FUNCTION IS ESSENTIAL FOR SURVIVAL OF ACUTE LYMPHOBLASTIC LEUKEMIA CELLS

E.A. Edwards, Dominic Schenone, Urmila Sivagnanalingam, Craig A. Mullen, S. Paul Perry
article en

Abstract

These studies demonstrate that acute lymphoblastic cell survival is impaired by interference with the gap junction function. The development of drugs targeting gap junctions may provide a novel approach to the therapy of acute lymphoblastic leukemia.

Experimental OncologyVol. 46(2)
University of Rochester (US)
Good health and well-being
Openalex Percentile: Top 84%
Connexins and lens biology
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GAP JUNCTION FUNCTION IS ESSENTIAL FOR SURVIVAL OF ACUTE LYMPHOBLASTIC LEUKEMIA CELLS — E.A. Edwards, Dominic Schenone, et al. · Experimental Oncology (2024) | TGRS Research Map | TGRS