Intestinal endogenous metabolites affect neuroinflammation in 5×FAD mice by mediating “gut-brain” axis and the intervention with Chinese Medicine
Together, our finding highlighted that the alternation in gut microbiota affected the effective communication between the "gut-brain" axis in 5×FAD mice by regulating the immune system, carbohydrate, and energy metabolism.
Authors
- Linna Wang
- Baolin Bian (ORCID: https://orcid.org/0000-0002-7792-3204)
- Xiaolu Wei (ORCID: https://orcid.org/0000-0001-9952-3757)
- Miao-Xuan Fan
- Yanyan Zhou (ORCID: https://orcid.org/0000-0001-5460-8917)
- Wenya Gao (ORCID: https://orcid.org/0000-0002-7324-8723)
- Haiyu Zhao (ORCID: https://orcid.org/0000-0003-0035-1874)
- Xinru Gu
- Hongjie Wang (ORCID: https://orcid.org/0000-0002-8243-2469)
- Tao Li (ORCID: https://orcid.org/0000-0002-7988-3090)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-4941-8622)
- Nan Si (ORCID: https://orcid.org/0000-0002-0656-2325)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s13195-024-01587-5
- Citations
- 19
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.44