HDAC10 inhibits non-small-cell lung cancer cell ferroptosis through the microRNA-223-5p-SLC7A11 axis
HDAC10 inhibits miR-223-5p expression through H3K9ac deacetylation of the miR-223-5p promoter, thereby promoting SLC7A11 expression and inhibiting ferroptosis in NSCLC cells.
Authors
- Liangbiao Peng
- X Sun
- Zhong Shi (ORCID: https://orcid.org/0009-0008-8712-0764)
- Tao Jiang (ORCID: https://orcid.org/0000-0002-3690-6678)
- Yi Wang (ORCID: https://orcid.org/0000-0003-1949-316X)
- Bingji Cao (ORCID: https://orcid.org/0009-0003-6457-3094)
Institutions
- Hebei Medical University (CN)
- The Fourth People's Hospital (CN)
- Fourth Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Toxicology Research
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1093/toxres/tfae164
- Citations
- 2
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.57