Pangolin scales as adaptations for innate immunity against pathogens
This study identifies a potential role of pangolin scales and implicates scales, as possible determinants of pathogen defense due to their structure and contents. We indicate for the first time the presence of exosomes in pangolin scales and propose the new functions of scales and their mechanisms. This new mechanism could have implications for multiple fields, including providing interesting new research directions and important insights that can be useful for synthesizing and implementing new biomimetic antimicrobial approaches.
Authors
- Klaus‐Peter Koepfli (ORCID: https://orcid.org/0000-0001-7281-0676)
- K. Lau (ORCID: https://orcid.org/0000-0002-6445-2407)
- Mu Wang (ORCID: https://orcid.org/0000-0002-5235-4914)
- Geok Yuan Annie Tan (ORCID: https://orcid.org/0000-0003-0112-7903)
- Jinfeng Zhou (ORCID: https://orcid.org/0000-0003-2479-3968)
- Jing Li (ORCID: https://orcid.org/0000-0001-5173-0781)
- Siew Woh Choo (ORCID: https://orcid.org/0000-0002-9210-3837)
- Xuechen Tian (ORCID: https://orcid.org/0000-0002-1256-2890)
- Nicholas S. Jakubovics (ORCID: https://orcid.org/0000-0001-6667-0515)
- Siyuan Zhang (ORCID: https://orcid.org/0000-0002-1307-2869)
- Lian Chen (ORCID: https://orcid.org/0000-0002-9741-022X)
- Enbo Wang (ORCID: https://orcid.org/0000-0002-4721-276X)
- Yixin Yang (ORCID: https://orcid.org/0000-0001-8214-8583)
- K.O. Song
Institutions
- George Mason University (US)
- Smithsonian Conservation Biology Institute (US)
- University of Malaya (MY)
- Wenzhou-Kean University (CN)
- Kean University (US)
- Xi’an Jiaotong-Liverpool University (CN)
- Newcastle University (GB)
Publication Details
- Journal
- BMC Biology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s12915-024-02034-5
- Citations
- 4
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.55