Prognostic impact of microscopic residual disease after neoadjuvant chemotherapy in patients undergoing interval debulking surgery for advanced ovarian cancer
Even in the absence of macroscopic disease after NACT, the persistence of microscopic residuals predicts a poorer prognosis among AEOC patients undergoing IDS, with a trend towards worse PFS for patients with more than three affected areas. Removing all fibrotic residuals eventually hiding microscopic disease during IDS represents the key to improving the prognosis of these patients.
Authors
- Andrea Giannini (ORCID: https://orcid.org/0000-0002-4388-0082)
- Giorgio Bogani (ORCID: https://orcid.org/0000-0001-8373-8569)
- Giuseppe Caruso (ORCID: https://orcid.org/0000-0001-5501-1936)
- Ludovico Muzii (ORCID: https://orcid.org/0000-0001-7195-9583)
- Tullio Golia D’Augè (ORCID: https://orcid.org/0000-0002-1018-3088)
- Angelina Pernazza (ORCID: https://orcid.org/0000-0002-8608-2734)
- Pierluigi Benedetti Panici (ORCID: https://orcid.org/0000-0001-6752-2039)
- Federica Tomao (ORCID: https://orcid.org/0000-0002-9738-3102)
- Violante Di Donato (ORCID: https://orcid.org/0000-0002-9254-5790)
- Innocenza Palaia (ORCID: https://orcid.org/0000-0003-2346-8696)
- Giorgia Perniola (ORCID: https://orcid.org/0000-0003-0321-9828)
- Carlo Della Rocca (ORCID: https://orcid.org/0000-0002-7176-5217)
Institutions
- Policlinico Umberto I (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2024-10-13
- DOI
- https://doi.org/10.1007/s00404-024-07775-w
- Citations
- 11
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.91