Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient

IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.

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Journal
Tropical Doctor
Published
2024-10-13
DOI
https://doi.org/10.1177/00494755241282365
Primary Topic
Vasculitis and related conditions
Type
article
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0.00
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article

Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient

Satyaki Ganguly, Vinay Rathore, Joydeep Samanta, Naman Mahesh Pathak et al.
Tropical Doctor
Vasculitis and related conditions
article

Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient

Satyaki Ganguly, Vinay Rathore, Joydeep Samanta, Naman Mahesh Pathak, Jyoti Aggarwal, K Donselaar van der Pant
article en

Abstract

IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission. We report a case of a 41-year old HIV patient who presented with palpable purpura, melaena and oedema and was diagnosed with IgA vasculitis with severe renal (crescentic glomerulonephritis), gastrointestinal and skin involvement. He was treated with immunosuppressive drugs and HAART which led to remission of disease. This case is unusual due to the presence of crescentic glomerulopathy and the requirement of immunosuppression for remission induction.

Tropical DoctorVol. 55(1)
All India Institute of Medical Sciences Raipur (IN)
Good health and well-being
Openalex Percentile: Top 67%
Vasculitis and related conditions
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