Semaglutide ameliorates Alzheimer's disease and restores oxytocin in APP/PS1 mice and human brain organoid models
Semaglutide can ameliorate Alzheimer's disease in pre-clinical models, suggesting the promising therapeutic potential in AD patients.
Authors
- Yingqian Zhang (ORCID: https://orcid.org/0000-0002-1208-6070)
- Yinbing Zhang
- Qixing Zhong (ORCID: https://orcid.org/0009-0003-0342-4415)
- Yao He (ORCID: https://orcid.org/0000-0002-4697-7250)
- Zhihui Zhong (ORCID: https://orcid.org/0000-0001-7892-9029)
- Aiping Tong (ORCID: https://orcid.org/0000-0002-3392-5443)
- Bangcheng Zhao (ORCID: https://orcid.org/0000-0003-4397-8001)
- Cheng Tang
- Qinxi Li (ORCID: https://orcid.org/0000-0003-2213-1549)
- Ting Zhang (ORCID: https://orcid.org/0000-0001-9231-1604)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Sichuan Provincial Architectural Design and Research Institute (China) (CN)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2024-10-13
- DOI
- https://doi.org/10.1016/j.biopha.2024.117540
- Citations
- 24
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 7.84
Funders
- National Natural Science Foundation of China
- Sichuan University
- National Key Research and Development Program of China