Proteomic and metabolomic profiles of plasma-derived Extracellular Vesicles differentiate melanoma patients from healthy controls
The results further support the continued investigation of circulating plasma-derived EVs as biomarkers in melanoma. Furthermore, the potential of combined proteo-metabolomic signatures for differentiation between disease stages may provide valuable insights into early detection, prognosis, and personalised treatment strategies.
Authors
- Arjun Ajaykumar
- Brendan S. Kelly (ORCID: https://orcid.org/0000-0002-3449-8017)
- M. Bruce Shields
- Michelle Wilson (ORCID: https://orcid.org/0000-0002-9106-2607)
- Stephanie M. Bollard (ORCID: https://orcid.org/0000-0003-3220-6903)
- Robert Milling (ORCID: https://orcid.org/0000-0002-2974-077X)
- Amanda McCann (ORCID: https://orcid.org/0000-0003-1911-3307)
- K O'Donnell
- Shirley Potter (ORCID: https://orcid.org/0000-0002-8762-6334)
- Cristina Casalou (ORCID: https://orcid.org/0000-0003-3198-2783)
- Jane Howard (ORCID: https://orcid.org/0000-0001-6565-6877)
- J. N. O'Reilly
- Kieran J. Wynne (ORCID: https://orcid.org/0000-0001-5759-5285)
- K. Triana
- DJ Tobin
- P A Kelly
- G Fenn
Institutions
- University College Dublin (IE)
- Mater Misericordiae University Hospital (IE)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-10-13
- DOI
- https://doi.org/10.1016/j.tranon.2024.102152
- Citations
- 14
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 3.27
Funders
- Canadian Institute for Theoretical Astrophysics
- Wellcome Trust
- Health Service Executive
- Science Foundation Ireland
- University College Dublin