Possibilities for diagnosing essential thrombocythemia at the stage of primary health care

This clinical case presents a 39-year-old woman diagnosed with essential thrombocythemia, accompanied by a review of the epidemiology, clinical and diagnostic criteria, and patient management strategies. The case also includes a discussion of potential complications and prognosis associated with the condition. The importance of thorough outpatient monitoring is emphasized, which should include regular assessments of clinical symptoms, changes in blood count parameters, bone marrow trephine biopsy, and molecular genetic testing for MPL and CALR gene mutations. The report highlights gaps in the current medical examination process, suggesting that addressing these deficiencies could improve early detection of essential thrombocythemia and enable timely pathogenetic therapy with antiplatelet agents to prevent complications.

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Publication Details

Journal
Russian Family Doctor
Published
2024-10-13
DOI
https://doi.org/10.17816/rfd630047
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Possibilities for diagnosing essential thrombocythemia at the stage of primary health care

V. S. Manto, Karen Arzumanyan, Vitaly V. Gorban, Nikita O. Bergen
Russian Family Doctor
Myeloproliferative Neoplasms: Diagnosis and Treatment
article

Possibilities for diagnosing essential thrombocythemia at the stage of primary health care

V. S. Manto, Karen Arzumanyan, Vitaly V. Gorban, Nikita O. Bergen
article en

Abstract

This clinical case presents a 39-year-old woman diagnosed with essential thrombocythemia, accompanied by a review of the epidemiology, clinical and diagnostic criteria, and patient management strategies. The case also includes a discussion of potential complications and prognosis associated with the condition. The importance of thorough outpatient monitoring is emphasized, which should include regular assessments of clinical symptoms, changes in blood count parameters, bone marrow trephine biopsy, and molecular genetic testing for MPL and CALR gene mutations. The report highlights gaps in the current medical examination process, suggesting that addressing these deficiencies could improve early detection of essential thrombocythemia and enable timely pathogenetic therapy with antiplatelet agents to prevent complications.

Russian Family DoctorVol. 28(3)
Kuban State Medical University (RU)
Good health and well-being
Openalex Percentile: Top 70%
Myeloproliferative Neoplasms: Diagnosis and Treatment
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Possibilities for diagnosing essential thrombocythemia at the stage of primary health care — V. S. Manto, Karen Arzumanyan, et al. · Russian Family Doctor (2024) | TGRS Research Map | TGRS