Relationship between Clinicopathological Factors of Breast Cancer and Lymph Node Metastasis in Young Women

Aim : To determine the incidence of lymph node metastasis in breast cancer of young women and its relationship with clinicopathologic factors. Methods : The study used an analytic observational design and a cross-sectional approach. Bivariate analysis was performed with Fisher's exact probability test to determine the association of clinicopathologic factors with lymph node metastasis. Results: N1 lymph node metastases could be found in most of the young women breast cancer patients at 42.9%, followed by N3 and N2 at 11.4% and 8.6%, respectively. On the other hand, 37.1% of patients showed no lymph node metastasis. Fisher's exact probability test showed that of the six clinicopathological factors, only tumour size was associated with lymph node metastasis with a p-value of 0.031. Conclusion : The incidence rate of lymph node metastasis in breast cancer of young women was 42.9% for N1, 11.4% for N3, and 8.6% for N2. There was a significant association between tumour size and lymph node metastasis.

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Publication Details

Journal
South Eastern European Journal of Public Health
Published
2024-09-21
DOI
https://doi.org/10.70135/seejph.vi.1317
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
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article

Relationship between Clinicopathological Factors of Breast Cancer and Lymph Node Metastasis in Young Women

Zuvar Faza Halim, Diani Kartini
South Eastern European Journal of Public Health
Endometrial and Cervical Cancer Treatments
article

Relationship between Clinicopathological Factors of Breast Cancer and Lymph Node Metastasis in Young Women

Zuvar Faza Halim, Diani Kartini
article en

Abstract

Aim : To determine the incidence of lymph node metastasis in breast cancer of young women and its relationship with clinicopathologic factors. Methods : The study used an analytic observational design and a cross-sectional approach. Bivariate analysis was performed with Fisher's exact probability test to determine the association of clinicopathologic factors with lymph node metastasis. Results: N1 lymph node metastases could be found in most of the young women breast cancer patients at 42.9%, followed by N3 and N2 at 11.4% and 8.6%, respectively. On the other hand, 37.1% of patients showed no lymph node metastasis. Fisher's exact probability test showed that of the six clinicopathological factors, only tumour size was associated with lymph node metastasis with a p-value of 0.031. Conclusion : The incidence rate of lymph node metastasis in breast cancer of young women was 42.9% for N1, 11.4% for N3, and 8.6% for N2. There was a significant association between tumour size and lymph node metastasis.

South Eastern European Journal of Public Health
University of Indonesia (ID), Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
Good health and well-being
Openalex Percentile: Top 72%
Endometrial and Cervical Cancer Treatments
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