Antifungal Properties of Eucalyptus Camaldulensis Essential Oil Against Aspergillus Spp

Eucalyptus Essential oils has a variety of bioactivities as fungicidal, bactericidal, insecticidal and other therapeutic properties . This investigation was conducted to assess the antifungal properties of Eucalyptus camaldulensis essential oil alone and in combination with clotrimazole against Aspergillus spp that isolated from patients. The in laboratory results appeared that the development of Aspergillus spp was discouraged by the essential oil at all tested concentration (100 , 50 and 25%) and the effect was increased with the increasing of concentration. The antifungal drugs clotrimazole , itraconzole and griseofulvin also affect the development of Aspergillus spp and the fungus A. fumigatus was less sensitive to essential oil and drugs than the other species of Aspergillus. The outcome shown that the combination of clotrimazol with essential oil was more effective than each one alone and the combination enhanced the antifungal activity with an additive interaction.