Jujuboside A Regulates Calcium Homeostasis and Structural Plasticity to Alleviate Depression-Like Behavior via Shh Signaling in Immature Neurons
These findings collectively suggest that JuA improves depressive-like behavior in CUMS rats by modulating calcium homeostasis and synaptic structural plasticity in immature neurons through the Shh signaling pathway.
Authors
- Yuanshan Han
- Hongping Long (ORCID: https://orcid.org/0000-0001-8891-5851)
- Pan Meng
- Yuhong Wang (ORCID: https://orcid.org/0000-0003-2285-6339)
- Mei Wu (ORCID: https://orcid.org/0000-0003-0952-5973)
- Jian Liu (ORCID: https://orcid.org/0000-0001-6877-9725)
- Yajing Wang (ORCID: https://orcid.org/0000-0002-6358-6948)
- Liu Yang (ORCID: https://orcid.org/0000-0003-0677-6152)
- Feng Qiu
- Lei Zhao (ORCID: https://orcid.org/0000-0002-8367-3045)
- Yan Luo
- Hongqing Zhao (ORCID: https://orcid.org/0000-0002-4423-0612)
- Ziyan Zhong
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/dddt.s479055
- Citations
- 8
- Primary Topic
- Ziziphus Jujuba Studies and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.79