Upfront Management of Blastoid Variant Mantle Cell Lymphoma: Making the Case for 2nd/3rd‐Generation Bruton Tyrosine Kinase Inhibitor‐Based Therapies

Treatment outcomes with chemo-immunotherapy in BV-MCL patients are poor, especially among TP53-mutated patients. Recent findings describing positive outcomes with novel BTKi-based therapies are encouraging and should be considered in this high-risk population.

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Publication Details

Journal
Cancer Medicine
Published
2024-10-01
DOI
https://doi.org/10.1002/cam4.70310
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Upfront Management of Blastoid Variant Mantle Cell Lymphoma: Making the Case for 2nd/3rd‐Generation Bruton Tyrosine Kinase Inhibitor‐Based Therapies

Elizabeth Brém, Shawn P. Griffin, Jean Doh, Piyanuch Kongtim et al.
5 links
Cancer Medicine
Lymphoma Diagnosis and Treatment
article

Upfront Management of Blastoid Variant Mantle Cell Lymphoma: Making the Case for 2nd/3rd‐Generation Bruton Tyrosine Kinase Inhibitor‐Based Therapies

Elizabeth Brém, Shawn P. Griffin, Jean Doh, Piyanuch Kongtim, Stefan O. Ciurea, Benjamin J. Lee, Jenny Liu
article en

Abstract

Treatment outcomes with chemo-immunotherapy in BV-MCL patients are poor, especially among TP53-mutated patients. Recent findings describing positive outcomes with novel BTKi-based therapies are encouraging and should be considered in this high-risk population.

Cancer MedicineVol. 13(19)
University of California, Irvine (US), UC Irvine Health (US)
No poverty
Openalex Percentile: Top 71%
Lymphoma Diagnosis and Treatment
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