Evaluation of single anastomosis sleeve ileal bypass in the treatment of morbidly obese patients with type 2 diabetes mellitus

Background: Laparoscopic single anastomosis sleeve ileal (SASI) bypass has recently evolved as a novel approach totreating both obesity and its associated comorbidities. This study aims to evaluate the efficacy and feasibility of SASIbypass in patients with obesity and type 2 diabetes mellitus (T2DM).Patients and Methods: We conducted a prospective study on 30 morbidly obese patients having T2DM between January2021 to September 2022. All the patients underwent laparoscopic SASI bypass, and all were followed for 12 months aftersurgery in terms of T2DM remission. Other parameters were also recorded and analyzed. The percentage of mean excessweight loss (EWL%) was evaluated and noted at each follow-up.Results: At 12 months, EWL% was 82%. All the patients evaluated had shown T2DM remission by 1 year (6.7% partialremission and 93.3% complete remission), with 77.8% remission of hypertension and 95.5% remission of dyslipidemia.Conclusion: SASI offers an excellent EWL% reduction, T2DM remission, and comorbidities resolution, and it should beconsidered an effective way to treat obesity in T2DM.