Photobiomodulation reduces spinal cord edema by decreasing the expression of AQP4 in the astrocytes of male spinal cord injury rats via the JAK2/STAT3 signaling pathway
These findings suggest that PBM reduces spinal cord swelling in rats after injury. This effect is associated with the inhibition of JAK2/STAT3 signaling pathway activation in astrocytes and the reduction in AQP4 expression.
Authors
- Xiaoshuang Zuo
- Yangguang Ma (ORCID: https://orcid.org/0000-0002-5758-4815)
- Xueyu Hu (ORCID: https://orcid.org/0000-0003-0852-1196)
- Xuankang Wang
- Tingyu Wu (ORCID: https://orcid.org/0009-0009-5172-5654)
- Zhihao Zhang (ORCID: https://orcid.org/0000-0002-3007-492X)
- Zhe Wang (ORCID: https://orcid.org/0009-0000-2387-784X)
- Jie Zhou (ORCID: https://orcid.org/0000-0001-7701-234X)
- Yong Yang (ORCID: https://orcid.org/0000-0002-1514-722X)
- Cheng Ju (ORCID: https://orcid.org/0000-0002-2282-6917)
Institutions
- Xi'an Medical University (CN)
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2024-10-12
- DOI
- https://doi.org/10.1016/j.pdpdt.2024.104364
- Primary Topic
- Hydrogen's biological and therapeutic effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Key Research and Development Projects of Shaanxi Province