Ancient viral DNA in the human genome linked to neurodegenerative diseases
We found HERV expression profiles robustly associated with amyotrophic lateral sclerosis and multiple sclerosis susceptibility, highlighting novel risk mechanisms underlying neurodegenerative disease, and offering potential new targets for therapeutic intervention.
Authors
- Rodrigo R. R. Duarte (ORCID: https://orcid.org/0000-0002-7666-9005)
- Douglas F. Nixon (ORCID: https://orcid.org/0000-0002-2801-1786)
- Timothy R. Powell (ORCID: https://orcid.org/0000-0001-9891-4895)
Institutions
- Feinstein Institute for Medical Research (US)
- King's College London (GB)
- Cornell University (US)
Publication Details
- Journal
- Brain Behavior and Immunity
- Published
- 2024-10-12
- DOI
- https://doi.org/10.1016/j.bbi.2024.10.020
- Citations
- 7
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- UK Research and Innovation
- Psychiatry Research Trust
- National Institutes of Health
- Medical Research Council