Hypothalamic tanycytes internalize ghrelin from the cerebrospinal fluid: Molecular mechanisms and functional implications
We propose that tanycyte-mediated transport of ghrelin is functionally relevant, as it may contribute to reduce the concentration of this peptide hormone in the CSF and consequently shortens the duration of its central effects.
Authors
- Gimena Fernández (ORCID: https://orcid.org/0000-0003-2742-157X)
- Maia Uriarte
- Sonia Cantel (ORCID: https://orcid.org/0000-0002-7583-8591)
- Mario Perelló (ORCID: https://orcid.org/0000-0003-2114-6765)
- Jean‐Alain Fehrentz (ORCID: https://orcid.org/0000-0002-6064-3118)
- Daniel C. Castrogiovanni (ORCID: https://orcid.org/0000-0001-8080-8509)
- Pablo Nicolás De Francesco (ORCID: https://orcid.org/0000-0003-4226-7507)
- Franco Barrile (ORCID: https://orcid.org/0000-0003-0620-2095)
- Ivana M Gomez
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Institut des Biomolécules Max Mousseron (FR)
- Instituto Multidisciplinario de Biología Celular (AR)
- Universidad Nacional de La Plata (AR)
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-10-12
- DOI
- https://doi.org/10.1016/j.molmet.2024.102046
- Citations
- 10
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 2.74
Funders
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Agencia Nacional de Promoción Científica y Tecnológica
- Fondo para la Investigación Científica y Tecnológica