PREDICTION OF THE STATE OF CRITICAL PATIENTS WITH SARS-CoV-2 INFECTION (LABORATORY ASPECT)

The aim of the study: to establish potential hematological markers for predicting mortality and recovery in patients with severe disease. Research metods. Demographic data, comorbidities, and blood parameters in patients with COVID-19 were analyzed. Critically ill COVID-19 patients have been divided into two research groups: those who recovered from a severe course of the disease (group 0) and deceased (group 1). Results and Conclusions. Clinical and laboratory hematocytological, biochemical, and hemostasis blood tests have been carried out. Diagnostic accuracy of several hematological indices has been established for prognostic stratification of the fatal outcome of the disease course in critical patients, namely the neutrophil-to-lymphocyte ratio (NLR > 5.57), the systemic immune- inflammation index (SII > 1914), enzyme activity determination (SPK > 137) and hemostasis parameters evaluation (D-dimer > 243; SFC > 6.5).