Osmotic Demyelination Syndrome: Trident Sign

A 72-year-old female experienced severe hyponatremia, leading to a serum sodium level of 102.5 mEq/L. Sodium levels were rapidly increased, resulting in osmotic demyelination syndrome (ODS). Magnetic resonance imaging is the most appropriate diagnostic tool for ODS, with the classic trident-shaped appearance formed by the hyperintense central pontine signal. Patients with ODS often require intensive supportive care and relowering of sodium levels.