Tertiary lymphoid structures and B-cell infiltration are IPF features with functional consequences
A prominent B-cell infiltration, along with the presence of TLS, the activity of which correlates with FVC decline, is an important component of IPF from the beginning of the disease, likely playing an important role on its mechanism and progression.
Authors
- Davide Biondini (ORCID: https://orcid.org/0000-0002-0726-0812)
- Elisabetta Balestro (ORCID: https://orcid.org/0000-0003-1373-8197)
- Simonetta Baraldo (ORCID: https://orcid.org/0000-0001-8923-7511)
- Nicol Bernardinello
- Elisabetta Cocconcelli (ORCID: https://orcid.org/0000-0002-0343-1565)
- Federica Pezzuto (ORCID: https://orcid.org/0000-0002-8023-3108)
- Erica Bazzan (ORCID: https://orcid.org/0000-0003-2956-0880)
- Fiorella Calabrese (ORCID: https://orcid.org/0000-0001-5351-9226)
- Giordano Fiorentù (ORCID: https://orcid.org/0009-0002-7400-0073)
- Federico Rea (ORCID: https://orcid.org/0000-0001-7988-5101)
- Marina Saetta (ORCID: https://orcid.org/0000-0002-1547-2102)
- Graziella Turato (ORCID: https://orcid.org/0000-0003-1895-6388)
- Alessandro Sanduzzi (ORCID: https://orcid.org/0000-0002-0977-2643)
- Mariaenrica Tinè (ORCID: https://orcid.org/0000-0002-3094-5721)
- Manuel G. Cosío
- Paolo Spagnolo
Institutions
- University of Padua (IT)
- Ospedale Monaldi (IT)
- Christie (Canada) (CA)
- McGill University (CA)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.3389/fimmu.2024.1437767
- Citations
- 16
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 6.70
Funders
- Università degli Studi di Padova