The impact of sleep problems on cerebral aneurysm risk is mediated by hypertension: a mediated Mendelian randomization study

The causal relationship between insomnia and CA was predicted using genetic variance data, and insomnia was found to be a potential risk factor. Furthermore, hypertension is a mediator between insomnia and CA. Therefore, focusing on sleep problems and improving sleep quality may be an active and effective strategy to prevent CA.

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Publication Details

Journal
Frontiers in Genetics
Published
2024-10-11
DOI
https://doi.org/10.3389/fgene.2024.1434189
Citations
1
Primary Topic
Moyamoya disease diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.47
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article

The impact of sleep problems on cerebral aneurysm risk is mediated by hypertension: a mediated Mendelian randomization study

Hongwu Li, Xiaofei Yan
1 citations
Frontiers in Genetics
Moyamoya disease diagnosis and treatment
0.47
article

The impact of sleep problems on cerebral aneurysm risk is mediated by hypertension: a mediated Mendelian randomization study

Hongwu Li, Xiaofei Yan
article en
1 citations

Abstract

The causal relationship between insomnia and CA was predicted using genetic variance data, and insomnia was found to be a potential risk factor. Furthermore, hypertension is a mediator between insomnia and CA. Therefore, focusing on sleep problems and improving sleep quality may be an active and effective strategy to prevent CA.

Frontiers in GeneticsVol. 15
Wenzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 31%
Moyamoya disease diagnosis and treatment
0.47
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The impact of sleep problems on cerebral aneurysm risk is mediated by hypertension: a mediated Mendelian randomization study — Hongwu Li, Xiaofei Yan · Frontiers in Genetics (2024) | TGRS Research Map | TGRS