Combined nephrotoxicity of Polymyxins and Vancomycin: a study on adverse event reporting for monotherapy versus combinations using the FDA adverse event reporting system (FAERS)

This study found that combining vancomycin with colistin alleviated colistin-induced nephrotoxicity, while combining vancomycin with polymyxin B worsened polymyxin B-induced nephrotoxicity.

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Publication Details

Journal
Expert Opinion on Drug Safety
Published
2024-10-11
DOI
https://doi.org/10.1080/14740338.2024.2416256
Citations
1
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
0.35
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article

Combined nephrotoxicity of Polymyxins and Vancomycin: a study on adverse event reporting for monotherapy versus combinations using the FDA adverse event reporting system (FAERS)

Xianxia He, Zhihui Jiang, Rixing Zhan, Bo Ji et al.
1 citations
Expert Opinion on Drug Safety
Pharmacovigilance and Adverse Drug Reactions
0.35
article

Combined nephrotoxicity of Polymyxins and Vancomycin: a study on adverse event reporting for monotherapy versus combinations using the FDA adverse event reporting system (FAERS)

Xianxia He, Zhihui Jiang, Rixing Zhan, Bo Ji, Dai Miao, Jiageng Lin
article en
1 citations

Abstract

This study found that combining vancomycin with colistin alleviated colistin-induced nephrotoxicity, while combining vancomycin with polymyxin B worsened polymyxin B-induced nephrotoxicity.

Expert Opinion on Drug SafetyVol. 25(1)
Guangzhou University of Chinese Medicine (CN), Center for Drug Evaluation and Research (US), National Medical Products Administration (CN), Third Affiliated Hospital of Southern Medical University (CN), Southern Command Hospital (IN), Southern Medical University (CN)
Openalex Percentile: Top 41%
Pharmacovigilance and Adverse Drug Reactions
0.35
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