Ventricular interdependent phenotype of mixed Cpc‐pulmonary hypertension and HFpEF with normal left atrium: Impact on CPET metrics and clinical outcomes
Among 45 CpcPH/heart failure with preserved ejection fraction participants, 11 with normal left atrium (compared to 34 with abnormal left atrium, <i>p</i> < 0.05 for all) had low left ventricle (LV) transmural pressure (2.9 ± 2.4 vs. 6.2 ± 2.9 mmHg), and increased right ventricle (RV):LV ratio (2.41 ± 1.09 vs. 1.46 ± 0.66) and interventricular septal angle (149 ± 8 vs. 136 ± 10), indicating exaggerated ventricular interdependence from a dilated RV.
Authors
- Mariana Garcia‐Arango (ORCID: https://orcid.org/0000-0001-5475-245X)
- Aurangzeb Baber (ORCID: https://orcid.org/0000-0002-9046-9237)
- Anas Ibrahim Abed (ORCID: https://orcid.org/0000-0003-2828-1011)
- Abdul Wahab Arif
- Sofia Carolina Masri (ORCID: https://orcid.org/0000-0002-4616-7928)
- Ahmed El Shaer (ORCID: https://orcid.org/0000-0002-3368-116X)
- Aditya Sahai (ORCID: https://orcid.org/0000-0003-1691-9604)
- Wanxin Tu (ORCID: https://orcid.org/0009-0005-2651-6317)
- Babak Tehrani
- Farhan Raza (ORCID: https://orcid.org/0000-0001-5750-2034)
- Shannon Heffernan
- James Runo (ORCID: https://orcid.org/0000-0001-8639-8643)
- Giovanna Zampierollo‐Jaramillo
- Yimin Chen (ORCID: https://orcid.org/0000-0002-1805-6665)
- A Esmaeeli
Institutions
- University of Wisconsin–Madison (US)
- Thomas Jefferson University (US)
Publication Details
- Journal
- Pulmonary Circulation
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/pul2.12449
- Citations
- 4
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- American Heart Association
- National Institutes of Health
- National Center for Advancing Translational Sciences