Assessment of Specific Biomarkers’ Profile and Structural, Functional Parameters of the Left Ventricle in Patients With Lymphomas Undergoing Antitumor Therapy
The study showed that patients with lymphoproliferative diseases had no signs of cardiotoxicity during PCT according to the accepted criteria. This study described and highlighted for the first time the interrelation of endothelial dysfunction, profibrotic status, and LV diastolic dysfunction as manifestations of cardiovascular toxicity in patients with lymphoproliferative diseases. It is advisable to supplement the integrated strategies for the prevention and monitoring of PCT cardiovascular toxicity with a thorough evaluation of instrumental parameters of diastolic dysfunction for timely initiation/correction of cardioprotective therapy.
Authors
- Yu. N. Belenkov (ORCID: https://orcid.org/0000-0002-3014-6129)
- Anastasia Shchendrygina (ORCID: https://orcid.org/0000-0002-8220-0350)
- S. A. Kardovskaya (ORCID: https://orcid.org/0000-0002-4220-7582)
- O. A. Zhigulina (ORCID: https://orcid.org/0000-0001-8118-2552)
- I. S. Ilgisonis (ORCID: https://orcid.org/0000-0001-6817-6270)
- T. Yu. Kulagina (ORCID: https://orcid.org/0000-0001-6165-6474)
- Svetlana A. Appolonova (ORCID: https://orcid.org/0000-0002-9032-1558)
- Н. В. Хабарова (ORCID: https://orcid.org/0000-0001-8843-2374)
- I. Ya. Sokolova (ORCID: https://orcid.org/0000-0002-8884-1087)
- Sh. M. Murtuzaliev (ORCID: https://orcid.org/0009-0001-8107-7557)
- Pavel A. Markin (ORCID: https://orcid.org/0000-0002-2240-2903)
Institutions
- Sechenov University (RU)
- City Clinical Hospital (RU)
- Russian Scientific Center of Surgery (RU)
Publication Details
- Journal
- Kardiologiia
- Published
- 2024-09-30
- DOI
- https://doi.org/10.18087/cardio.2024.9.n2743
- Citations
- 2
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.80