Comparative Analysis of The Effectiveness of Antihypertensive Therapy Including Spironolactone and Eplerenone in Patients With Essential Hypertension and Atrial Fibrillation
The good antihypertensive efficacy of the 6-month combination therapy containing eplerenone was significantly superior to spironolactone in achieving the target BP values. The eplerenone-containing treatment significantly improved LVEF and decreased LAVI compared to the spironolactone-containing treatment. A trend towards a beneficial effect of the AHT containing eplerenone on concentrations of sex hormones was noted in both women and men.
Authors
- Г М Раджабова
- M Khatamova
- Р Алиева (ORCID: https://orcid.org/0000-0003-3936-0815)
- Muazzam Pulatova (ORCID: https://orcid.org/0009-0007-7027-1294)
- Г. Ж. Абдуллаева (ORCID: https://orcid.org/0000-0003-3840-5233)
- Nigora Sherbadalova (ORCID: https://orcid.org/0009-0004-2185-7238)
- N. N. Ibragimov
- Zarina Mashkurova
Institutions
- Tashkent Pediatric Medical Institute (UZ)
Publication Details
- Journal
- Kardiologiia
- Published
- 2024-09-30
- DOI
- https://doi.org/10.18087/cardio.2024.9.n2712
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00