Assessing prospective molecular biomarkers and functional pathways in severe asthma based on a machine learning method and bioinformatics analyses
Mitochondrial abnormalities affecting oxidative phosphorylation play a critical role in severe asthma. Key molecular biomarkers like TFCP2L1, KRT6A, FCER1A, and CCL5, are essential for detecting severe asthma. This research significantly enhances the understanding and diagnosis of severe asthma.
Authors
- Ya-Da Zhang
- Binqing Tang (ORCID: https://orcid.org/0000-0002-0573-7816)
- Wei Zhang (ORCID: https://orcid.org/0000-0001-7673-1924)
- Yiren Chen (ORCID: https://orcid.org/0000-0003-0618-8457)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1080/02770903.2024.2409991
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.42