In Search of Optimal Criteria for Iron Deficiency in CHF Patients. Post-hoc Analysis of the Study “Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (ID-CHF-RF)”

Patients with isolated low ferritin are characterized by less severe clinical and functional impairment compared to patients with low TSAT or Fe. At the same time, patients with ferritin higher than 300 μg/l and low TSAT and/or Fe were characterized by very severe CHF and a low functional status, although this may not be related with ID. Thus, the use of the ferritin-based criteria of ID may lead to overdiagnosis of ID in some patients and, at the same time, miss some of the most "severe" patients who likely require the ID correction. Patients with ID who show a decrease in all three parameters are likely to benefit most from Fe supplementation. It is advisable to perform additional studies on the effect of Fe supplements on the course and prognosis of the disease in this cohort of patients.

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Publication Details

Journal
Kardiologiia
Published
2024-09-30
DOI
https://doi.org/10.18087/cardio.2024.9.n2732
Citations
1
Primary Topic
Erythropoietin and Anemia Treatment
Type
article
Field-Weighted Citation Impact
0.45
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article

In Search of Optimal Criteria for Iron Deficiency in CHF Patients. Post-hoc Analysis of the Study “Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (ID-CHF-RF)”

Елена Киселева, Yu. V. Mareev, Yu. V. Kotovskaya, О. Л. Барбараш et al.
1 citations
Kardiologiia
Erythropoietin and Anemia Treatment
0.45
article

In Search of Optimal Criteria for Iron Deficiency in CHF Patients. Post-hoc Analysis of the Study “Prevalence of Iron Deficiency in Patients With Chronic Heart Failure in the Russian Federation (ID-CHF-RF)”

Елена Киселева, Yu. V. Mareev, Yu. V. Kotovskaya, О. Л. Барбараш, Mareev VIu, L. V. Baleeva, E. V. Sedykh, А. А. Ефремушкина, M. A. Fedin, А. S. Galyavich, A. A. Lapshin, Yа. A. Orlova, Е. А. Смирнова, Н. А. Макарова, E.R. Kazakhmedov, Н. А. Козиолова, А. В. Фендрикова, Dmitry Viktorovich Duplyakov, A. A. Zemlyanukhina, И. И. Шапошник, E. M. Seredenina, Гарганеева Алла Анатольевна, L. V. Karapetyan, M. N. Maksimova, Kseniia A. Eruslanova, О. Н. Ткачева, T. B. Pecherina, С. А. Галочкин, Кужелева Елена Андреевна, Yu. L. Begrambekova, A. S. Veclich, N. A. Spiropoulos, S. S. Yakushin, З. М. Галеева, Ж. Д. Кобалава, V. V. Skibitsky, A. V. Skibitsky
article en
1 citations

Abstract

Patients with isolated low ferritin are characterized by less severe clinical and functional impairment compared to patients with low TSAT or Fe. At the same time, patients with ferritin higher than 300 μg/l and low TSAT and/or Fe were characterized by very severe CHF and a low functional status, although this may not be related with ID. Thus, the use of the ferritin-based criteria of ID may lead to overdiagnosis of ID in some patients and, at the same time, miss some of the most "severe" patients who likely require the ID correction. Patients with ID who show a decrease in all three parameters are likely to benefit most from Fe supplementation. It is advisable to perform additional studies on the effect of Fe supplements on the course and prognosis of the disease in this cohort of patients.

KardiologiiaVol. 64(9)
Altai State Medical University (RU), Peoples' Friendship University of Russia (RU), Kuban State Medical University (RU), Kazan State Medical University (RU), Lomonosov Moscow State University (RU), Chelyabinsk State Medical Academy (RU), Pirogov Russian National Research Medical University (RU), Perm State Medical Academy (RU), Regional Clinical Hospital No 4 (RU), Tomsk National Research Medical Center (RU), Samara State Medical University (RU), Ryazan State Medical University named after Academician I.P. Pavlov (RU), Moscow State University (TJ), Samara Regional Clinical Oncology Center (RU), Kemerovo State University (RU)
Good health and well-being
Openalex Percentile: Top 32%
Erythropoietin and Anemia Treatment
0.45
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