Dynamic BMP gene expression regulation in chick RPE during recovery from short term optical defocus and form-deprivation
The observed changes in BMP gene expression in chick RPE imply dynamic, albeit complex regulation, with the duration of exposure and recovery being critical variables for all three types of visual manipulations. This study provides further evidence for a role of the RPE as an important signal relay linking the retina to the choroid and sclera in eye growth regulation.
Authors
- Kiana Cheung
- Grace May Chuang (ORCID: https://orcid.org/0000-0001-7595-4501)
- Andreana Chou
- Christine F. Wildsoet (ORCID: https://orcid.org/0000-0003-2671-2391)
- Wulian Song (ORCID: https://orcid.org/0000-0003-0047-6917)
- Andrea He (ORCID: https://orcid.org/0000-0001-7869-3415)
- Daniel Sun (ORCID: https://orcid.org/0000-0001-7119-6045)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-6953-7127)
- Elham Shoghi
- Qiurong Zhu
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- Harbin Medical University (CN)
- Smith-Kettlewell Eye Research Institute (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1371/journal.pone.0311505
- Citations
- 2
- Primary Topic
- Ophthalmology and Visual Impairment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.77