Glucagon-Like Peptide-1 Receptor Agonist Use is Not Associated With Increased Complications After Total Knee Arthroplasty in Patients With Type-2 Diabetes

This study found that GLP-1 agonist use was not associated with increased medical or surgical complication rates in patients with diabetes undergoing TKA and was associated with lower rates of extended hospital stays after surgery. Given the potential for increased glycemic control and weight loss in patients using GLP-1 agonists, more data are needed to delineate the potential role of GLP-1 agonists in preoperative optimization of patients with diabetes prior to joint arthroplasty to minimize postoperative complications.

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Publication Details

Journal
Arthroplasty Today
Published
2024-10-11
DOI
https://doi.org/10.1016/j.artd.2024.101506
Citations
18
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
6.44
Controls
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article

Glucagon-Like Peptide-1 Receptor Agonist Use is Not Associated With Increased Complications After Total Knee Arthroplasty in Patients With Type-2 Diabetes

Brian T. Muffly, J Scott Holmes, Kevin Heo, Greg A. Erens et al.
18 citations
Arthroplasty Today
Diabetes Treatment and Management
6.44
article

Glucagon-Like Peptide-1 Receptor Agonist Use is Not Associated With Increased Complications After Total Knee Arthroplasty in Patients With Type-2 Diabetes

Brian T. Muffly, J Scott Holmes, Kevin Heo, Greg A. Erens, Jacob M. Wilson, Andrew Fuqua, Rahul Goel, Ajay Premkumar
article en
18 citations

Abstract

This study found that GLP-1 agonist use was not associated with increased medical or surgical complication rates in patients with diabetes undergoing TKA and was associated with lower rates of extended hospital stays after surgery. Given the potential for increased glycemic control and weight loss in patients using GLP-1 agonists, more data are needed to delineate the potential role of GLP-1 agonists in preoperative optimization of patients with diabetes prior to joint arthroplasty to minimize postoperative complications.

Arthroplasty TodayVol. 30
Hospital for Special Surgery (US), Emory University (US), Duke University (US)
Good health and well-being
Openalex Percentile: Top 3%
Diabetes Treatment and Management
6.44
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