The role of 27-hydroxycholesterol in hypercholesterolemia-associated exacerbation of apical periodontitis and therapeutic potential of felodipine
Our results suggest a pivotal role of 27HC in hypercholesterolemia-exacerbated AP. By repressing 27HC production, felodipine may have the potential to help mitigate AP in obese individuals.
Authors
- Shih‐Jung Cheng (ORCID: https://orcid.org/0000-0003-4674-4892)
- Chia‐Tung Shun (ORCID: https://orcid.org/0000-0002-0468-4468)
- Sang‐Heng Kok (ORCID: https://orcid.org/0000-0001-6445-8852)
- Hung‐Ying Lin (ORCID: https://orcid.org/0000-0002-3699-4516)
- Hanwei Wang (ORCID: https://orcid.org/0000-0001-9926-1144)
- Sze‐Kwan Lin (ORCID: https://orcid.org/0000-0002-7969-0280)
- Cheng-Ning Yang
- Fang‐Yu Wu
- Chi‐Yuan Hong (ORCID: https://orcid.org/0000-0002-4465-8440)
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Journal of Dental Sciences
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1016/j.jds.2024.09.027
- Citations
- 1
- Primary Topic
- Cholesterol and Lipid Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Ministry of Science and Technology, Taiwan
- National Taiwan University Hospital
- National Taiwan University
- National Science and Technology Council