Risk of cellular or antibody-mediated rejection in pediatric kidney transplant recipients with BK polyomavirus replication—an international CERTAIN registry study
These data indicate that reduction of immunosuppression for BKPyV-DNAemia management is associated with increased alloimmune response in pediatric KTR. Therefore, regular dnDSA screening and close monitoring of graft function in case of BKPyV-DNAemia followed by subsequent reduction of immunosuppressive therapy are recommended.
Authors
- Alexander Fichtner (ORCID: https://orcid.org/0000-0002-9939-4059)
- Andrea Carraro (ORCID: https://orcid.org/0000-0001-9564-9491)
- Jun Oh (ORCID: https://orcid.org/0000-0003-1846-675X)
- Atif Awan (ORCID: https://orcid.org/0000-0002-1615-2602)
- Lutz T. Weber (ORCID: https://orcid.org/0000-0003-4116-598X)
- Paul Schnitzler (ORCID: https://orcid.org/0000-0001-5503-3801)
- Sabine König
- Hans Hellmuth Hirsch (ORCID: https://orcid.org/0000-0003-0883-0423)
- Caner Süsal (ORCID: https://orcid.org/0000-0003-2521-8201)
- Kai Krupka (ORCID: https://orcid.org/0000-0002-0409-5196)
- Isabella Guzzo (ORCID: https://orcid.org/0000-0003-4960-3083)
- Matthias Zirngibl (ORCID: https://orcid.org/0000-0003-3661-6176)
- Jeremy Schmidt (ORCID: https://orcid.org/0000-0002-3816-7194)
- Britta Höcker (ORCID: https://orcid.org/0000-0003-4131-2273)
- Burkhard Tönshoff
Institutions
- Koç University (TR)
- University of Padua (IT)
- University of Cologne (DE)
- University of Basel (CH)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Hospital of Basel (CH)
- Temple Street Children's University Hospital (IE)
- University Hospital Münster (DE)
- Kinderkrebs-Zentrum Hamburg (DE)
- Bambino Gesù Children's Hospital (IT)
- University Children's Hospital Tübingen (DE)
- University Hospital Cologne (DE)
Publication Details
- Journal
- Pediatric Nephrology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1007/s00467-024-06501-7
- Citations
- 3
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Dietmar Hopp Stiftung
- Universitätsklinikum Heidelberg