Elevated serum IL-17 A and CCL20 levels as potential biomarkers in major psychotic disorders: a case-control study

The current study revealed that the serum levels of IL-17 A and CCL20 in schizophrenia patients are higher than those in the control group. Metabolic factors such as FBS, cholesterol, HDL, and LDL also showed significant differences between MPD and HC. In conclusion, the findings suggest that these two inflammatory factors could serve as potential therapeutic targets and prognostic biomarkers for schizophrenia.

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Publication Details

Journal
BMC Psychiatry
Published
2024-10-11
DOI
https://doi.org/10.1186/s12888-024-06032-3
Citations
10
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
2.40

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article

Elevated serum IL-17 A and CCL20 levels as potential biomarkers in major psychotic disorders: a case-control study

Somayeh Ghorbani, Zanireh Salimi, Parisa Ghasemi Noghabi, Najmeh Shahini et al.
10 citations
BMC Psychiatry
Psoriasis: Treatment and Pathogenesis
2.40
article

Elevated serum IL-17 A and CCL20 levels as potential biomarkers in major psychotic disorders: a case-control study

Somayeh Ghorbani, Zanireh Salimi, Parisa Ghasemi Noghabi, Najmeh Shahini, Yasser Bagheri, Firoozeh Derakhshanpour
article en
10 citations

Abstract

The current study revealed that the serum levels of IL-17 A and CCL20 in schizophrenia patients are higher than those in the control group. Metabolic factors such as FBS, cholesterol, HDL, and LDL also showed significant differences between MPD and HC. In conclusion, the findings suggest that these two inflammatory factors could serve as potential therapeutic targets and prognostic biomarkers for schizophrenia.

BMC PsychiatryVol. 24(1)
Mashhad University of Medical Sciences (IR), Golestan University (IR), Gonabad University of Medical Sciences (IR), Golestan University of Medical Sciences (IR)
Golestan University of Medical Sciences
Good health and well-being
Openalex Percentile: Top 11%
Psoriasis: Treatment and Pathogenesis
2.40
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