Tocilizumab in the treatment of COVID-19 related encephalopathy with Claustrum lesion: A case report
COVID-19-related encephalopathy is a complication of COVID-19 that affects the brain. It can present with symptoms such as altered mental status, ranging from mild confusion to deep coma. It is a major and devastating complication of the SARS-CoV-2 virus. COVID-19-related neurological symptoms may be associated with cytokine release induced by the virus, and tocilizumab targeting IL-6 receptor may provide significant benefits. We report a case of COVID-19-related encephalopathy with cerebrospinal fluid analysis revealing significantly elevated levels of IL-6. Brain magnetic resonance imaging showed a bilateral high signal in the claustrum, and treatment with tocilizumab was effective.
Authors
- Gaiqing Yang
- Ning Wang (ORCID: https://orcid.org/0000-0003-1745-1425)
- Chenhui Liu (ORCID: https://orcid.org/0000-0003-0098-3126)
- Hongzhi Guan (ORCID: https://orcid.org/0000-0003-3903-5078)
- Xiaochang Li (ORCID: https://orcid.org/0009-0009-9343-1478)
- Manman Zhou
- Q X Hu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Zhengzhou Central Hospital (CN)
Publication Details
- Journal
- Radiology Case Reports
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1016/j.radcr.2024.09.092
- Citations
- 1
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- Science and Technology Department, Henan Province