<i>In vitro</i> and <i>in vivo</i> performance of amorphous solid dispersions of ursolic acid as a function of polymer type and excipient addition
The research indicated that the multielement ASD could be employed as an efficacious drug delivery system for UA. Furthermore, the Soluplus/TPGS/choline combination represents a promising candidate for the fabrication of ASDs that can load weakly acidic and poorly soluble drugs.
Authors
- Fujiang Guo (ORCID: https://orcid.org/0000-0003-4073-4773)
- Yajun Wang (ORCID: https://orcid.org/0000-0002-2602-6327)
- Jianbo Qi
- Yiming Li (ORCID: https://orcid.org/0000-0003-3416-1331)
- Jingwen Liu (ORCID: https://orcid.org/0000-0002-0748-7830)
- Xiaojing Chen (ORCID: https://orcid.org/0000-0002-6378-4514)
- Chenming Gu
- Tingting Zhao
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1093/jpp/rgae125
- Citations
- 1
- Primary Topic
- Natural product bioactivities and synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.23