Chrysene contribution to bronchial asthma: Activation of TRPA1 disrupts bronchial epithelial barrier via ERK pathway
Our findings showed that chrysene contributed to the breakdown of the function of the bronchial epithelial barrier through the TRPA1-ERK axis and therefore acted as an adjuvant to contribute to asthma.
Authors
- Yuan Gao (ORCID: https://orcid.org/0000-0002-0670-9104)
- Han Dong
- Xinjia Zhou
- Xiaoyu Zhao
Institutions
- China Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1016/j.ecoenv.2024.117095
- Citations
- 3
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 1.08
Funders
- National Natural Science Foundation of China