Association of fluoroquinolones with the risk of spontaneous pneumothorax: nationwide case–time–control study
An increased risk of spontaneous pneumothorax was associated with both fluoroquinolone and amoxicillin use, with an even higher association for amoxicillin. This strongly suggests the role of the underlying infections rather than a causal effect of the individual antibiotics and can be considered reassuring regarding a potential lung connective toxicity of fluoroquinolones.
Authors
- Anne Bénard‐Laribière (ORCID: https://orcid.org/0000-0002-9071-6314)
- Alexandre Pariente (ORCID: https://orcid.org/0000-0002-7873-5483)
- S. Kouzan
- Julien Bezin (ORCID: https://orcid.org/0000-0002-2568-1928)
- Jean‐Luc Faillie (ORCID: https://orcid.org/0000-0003-0100-4073)
- Élodie Pambrun
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Université de Montpellier (FR)
- Centre Hospitalier Universitaire de Bordeaux (FR)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Bordeaux Population Health (FR)
- Centre Hospitalier Métropole Savoie (FR)
- Institute for Neurosciences of Montpellier (FR)
- Institut Desbrest d'Epidémiologie et de Santé Publique
Publication Details
- Journal
- Thorax
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1136/thorax-2024-221779
- Citations
- 4
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.55