Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment

This case demonstrates an unusual presentation of EDG in a young patient with granulomatous anterior and intermediate uveitis, where simple office-based procedures of Argon laser photocoagulation and anterior chamber paracentesis helped aid in diagnosis and management. Histopathological examination in serial specimens demonstrated the effect of 5-FU on EGD. To our knowledge, this case is the first to describe histopathological reduction in epithelial cell burden with sustained resolution.

Authors

Institutions

Publication Details

Journal
PubMed
Published
2024-09-23
DOI
https://doi.org/10.3205/oc000245
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment

Gordana Juric‐Sekhar, Colin P. Froines, C. Dirk Keene, Caitlin S. Latimer et al.
PubMed
Histiocytic Disorders and Treatments
article

Epithelial downgrowth masquerading as granulomatous anterior and intermediate uveitis with histopathologic evidence of 5-FU treatment

Gordana Juric‐Sekhar, Colin P. Froines, C. Dirk Keene, Caitlin S. Latimer, Alexander Lin, Michael R. Banitt, Kaivon Pakzad-Vaezi, Luis F. Gonzalez‐Cuyar, Kathryn P. Scherpelz, Eissa Hanna
article en

Abstract

This case demonstrates an unusual presentation of EDG in a young patient with granulomatous anterior and intermediate uveitis, where simple office-based procedures of Argon laser photocoagulation and anterior chamber paracentesis helped aid in diagnosis and management. Histopathological examination in serial specimens demonstrated the effect of 5-FU on EGD. To our knowledge, this case is the first to describe histopathological reduction in epithelial cell burden with sustained resolution.

PubMedVol. 14
University of British Columbia (CA), University of Washington (US), Kaiser Foundation Hospital (US), Northwest Eye Surgeons (US), Wellish Vision Institute (US)
Research to Prevent Blindness
Openalex Percentile: Top 75%
Histiocytic Disorders and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.