Effects of SGLT2 inhibitors on the onset of esophageal varices and extrahepatic cancer in type 2 diabetic patients with suspected MASLD: a nationwide database study in Japan
SGLT2i was more beneficial than DPP4i in improving the hepatic inflammation and fibrosis indices. Moreover, SGLT2i suppressed the incidence of esophageal varices and extrahepatic cancer compared to DPP4i. SGLT2i may suppress life-threatening events in patients with T2DM and suspected MASLD.
Authors
- Fusayo Io
- Yuri Sato (ORCID: https://orcid.org/0000-0003-0809-5000)
- Yoshiyuki Fujishima
- Daisuke Wakasugi
- Takumi Kawaguchi (ORCID: https://orcid.org/0000-0002-7064-4325)
- Saeko Uchida
- Yukiko Kitajima
Institutions
- Kurume University (JP)
- Taisho Pharmaceutical (Japan) (JP)
Publication Details
- Journal
- Journal of Gastroenterology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1007/s00535-024-02158-z
- Citations
- 26
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 10.05