The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets

The expression of the PD-L1 and MET genes is remarkably associated with worse tumor clinicopathologic features and poor prognosis in patients with breast cancer. Further investigations using combination drug regimens targeting PD-L1 and MET are important, particularly in breast tumors expressing high levels of both proteins.

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Journal
Current Cancer Drug Targets
Published
2024-10-11
DOI
https://doi.org/10.2174/0115680096333231240902070108
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
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article

The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets

Nehad M. Ayoub, Aymen Shatnawi, Laith Naser AL-Eitan, Moath Al-Shorman et al.
Current Cancer Drug Targets
Cancer, Lipids, and Metabolism
article

The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets

Nehad M. Ayoub, Aymen Shatnawi, Laith Naser AL-Eitan, Moath Al-Shorman, Muhsen Al-Diabat
article en

Abstract

The expression of the PD-L1 and MET genes is remarkably associated with worse tumor clinicopathologic features and poor prognosis in patients with breast cancer. Further investigations using combination drug regimens targeting PD-L1 and MET are important, particularly in breast tumors expressing high levels of both proteins.

Current Cancer Drug TargetsVol. 25(10)
Medical University of South Carolina (US), Jordan University of Science and Technology (JO)
Good health and well-being
Openalex Percentile: Top 74%
Cancer, Lipids, and Metabolism
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The Clinicopathological and Prognostic Significance of the Expression of PD-L1 and MET Genes in Breast Cancer: Potential Therapeutic Targets — Nehad M. Ayoub, Aymen Shatnawi, et al. · Current Cancer Drug Targets (2024) | TGRS Research Map | TGRS