Discovery of 5-(Substituted Phenyl)-2-aryl Benzimidazole Derivatives as SIRT1 Activators: Their Design, In silico Studies, Synthesis, and In vitro Evaluation
According to the findings, synthesized compounds may be viable leads for SIRT1 activators and may be used to advance preclinical in vivo research utilizing animal models.
Authors
- Deepika Saini (ORCID: https://orcid.org/0000-0002-8742-2411)
- Shilpi Chauhan (ORCID: https://orcid.org/0000-0002-9074-4390)
- Ashwani Kumar (ORCID: https://orcid.org/0000-0002-8966-3569)
- Rajnish Kumar (ORCID: https://orcid.org/0000-0002-5846-6837)
Institutions
- Guru Jambheshwar University of Science and Technology (IN)
- Banaras Hindu University (IN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2024-10-11
- DOI
- https://doi.org/10.2174/0109298673330534240924104941
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00