<scp>SOXC</scp> Enhances <scp>NGN2</scp>‐Mediated Reprogramming of Glioblastoma Cells Into Neuron‐Like Cells by Modulating <scp>RhoA</scp> and <scp>RAC1</scp>/<scp>CDC42</scp> Pathway Activity

These results underscore the pivotal role of SOXC factors' transcriptional repression and illuminate one of their specific downstream targets.

Authors

Ying Zhang (ORCID: https://orcid.org/0000-0001-9271-6193)
Jianjing Yang (ORCID: https://orcid.org/0000-0001-9416-1195)
Chun‐Li Zhang (ORCID: https://orcid.org/0000-0002-2639-4605)
Xiaohong Zhu (ORCID: https://orcid.org/0000-0003-2400-4199)
Qichuan Zhuge (ORCID: https://orcid.org/0000-0003-1431-4556)
Haoqi Ni
Jiawei Chen (ORCID: https://orcid.org/0009-0008-0141-5589)
Fan Wang (ORCID: https://orcid.org/0000-0002-3278-4319)
Zhen Chen (ORCID: https://orcid.org/0000-0002-4502-0801)

Institutions

Wenzhou Medical University (CN)
First Affiliated Hospital of Wenzhou Medical University (CN)
The University of Texas Southwestern Medical Center (US)

Publication Details

Journal: CNS Neuroscience & Therapeutics
Published: 2024-10-01
DOI: https://doi.org/10.1111/cns.70075
Citations: 1
Primary Topic: RNA Interference and Gene Delivery
Type: article
Field-Weighted Citation Impact: 0.23

Funders

National Natural Science Foundation of China

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article

SOXC Enhances NGN2‐Mediated Reprogramming of Glioblastoma Cells Into Neuron‐Like Cells by Modulating RhoA and RAC1/CDC42 Pathway Activity

Ying Zhang, Jianjing Yang, Chun‐Li Zhang, Xiaohong Zhu et al.

Oct 1, 2024

1 citations

CNS Neuroscience & Therapeutics

RNA Interference and Gene Delivery

0.23

article

SOXC Enhances NGN2‐Mediated Reprogramming of Glioblastoma Cells Into Neuron‐Like Cells by Modulating RhoA and RAC1/CDC42 Pathway Activity

Ying Zhang, Jianjing Yang, Chun‐Li Zhang, Xiaohong Zhu, Qichuan Zhuge, Haoqi Ni, Jiawei Chen, Fan Wang, Zhen Chen

October 1, 2024article en

1 citations

Abstract

These results underscore the pivotal role of SOXC factors' transcriptional repression and illuminate one of their specific downstream targets.

CNS Neuroscience & TherapeuticsVol. 30(10)

Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN), The University of Texas Southwestern Medical Center (US)

National Natural Science Foundation of China

Openalex Percentile: Top 42%

RNA Interference and Gene Delivery

0.23

DOI Open Access PDF OpenAlex

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<scp>SOXC</scp> Enhances <scp>NGN2</scp>‐Mediated Reprogramming of Glioblastoma Cells Into Neuron‐Like Cells by Modulating <scp>RhoA</scp> and <scp>RAC1</scp>/<scp>CDC42</scp> Pathway Activity — Ying Zhang, Jianjing Yang, et al. · CNS Neuroscience & Therapeutics (2024) | TGRS Research Map | TGRS