Combination of low-dose, long-term immunoglobulin and mirtazapine is effective in progressive multifocal leukoencephalopathy caused by JC virus infection
We demonstrated that the combination treatment of IVIG and mirtazapine was effective in PML. Low-dose, long-term immunoglobulin might regulate the immune status in our case with controlled inflammatory reaction instead of destructive virus spreading. The therapy may be a prospective option for PML.
Authors
- Jinsheng Zeng (ORCID: https://orcid.org/0009-0007-9593-3848)
- Shihui Xing (ORCID: https://orcid.org/0000-0002-2687-0640)
- Yuhua Fan (ORCID: https://orcid.org/0000-0002-1172-1490)
- Bing Liao (ORCID: https://orcid.org/0000-0002-1346-4125)
- Jinɡjinɡ Li (ORCID: https://orcid.org/0000-0002-7526-5308)
- Zhiyun Yang (ORCID: https://orcid.org/0009-0000-2787-1234)
- Jian Zhang (ORCID: https://orcid.org/0000-0002-4372-2826)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1186/s12883-024-03902-x
- Citations
- 3
- Primary Topic
- Polyomavirus and related diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Guangzhou Science and Technology Program key projects