Efferocytosis dysfunction in CXCL4-induced M4 macrophages: phenotypic insights in systemic sclerosis in vitro and in vivo
Altogether, our results support the role of CXCL4 on the impaired efferocytosis capacities of human macrophages from SSc patients and in SSc mice.
Authors
- Alice Ballerie (ORCID: https://orcid.org/0000-0002-0335-3974)
- C. Cazalets
- Claudie Morzadec
- Frédéric Gros (ORCID: https://orcid.org/0000-0002-6252-4323)
- Erwan Le Tallec (ORCID: https://orcid.org/0009-0002-5768-3159)
- Quentin Frenger (ORCID: https://orcid.org/0000-0002-2057-3813)
- Valérie Lecureur (ORCID: https://orcid.org/0000-0002-8606-4755)
- Nessrine Bellamri
- M Lelong
- Alain Lescoat (ORCID: https://orcid.org/0000-0003-2081-8558)
Institutions
- Inserm (FR)
- Institut de Recherche en Santé, Environnement et Travail (FR)
- Hôpital Pontchaillou (FR)
- Centre Hospitalier Universitaire de Rennes (FR)
- Immuno-Rhumathologie moléculaire
- Université de Rennes (FR)
- Université de Strasbourg (FR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.3389/fimmu.2024.1468821
- Citations
- 7
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.97
Funders
- Institut National de la Santé et de la Recherche Médicale
- Centre Hospitalier Universitaire de Rennes