Improved Prognosis in HER2-Low Breast Cancer Patients with Reduced Ki67 Index After Neoadjuvant Chemotherapy: A Multi-Center Retrospective Study
Our study demonstrates that HER2-low breast cancer patients with δKi67 values below the cut-off point after NAC are associated with improved prognosis. Monitoring δKi67 index and HER2 status may help identify patients who are likely to benefit from NAC and guide personalized treatment strategies.
Authors
- Cheng Tian (ORCID: https://orcid.org/0000-0003-4046-2288)
- Qiang Song (ORCID: https://orcid.org/0000-0002-3151-4122)
- Yudi Jin (ORCID: https://orcid.org/0000-0002-2836-0855)
- Yanjia Fan
- Yu Zhang (ORCID: https://orcid.org/0000-0002-3217-0245)
- Chi Zhang (ORCID: https://orcid.org/0000-0002-6729-1426)
- Mengyuan Wang (ORCID: https://orcid.org/0000-0003-2077-361X)
- Shengchun Liu (ORCID: https://orcid.org/0000-0003-4824-8235)
- Man Huang (ORCID: https://orcid.org/0000-0003-1358-2567)
Institutions
- Chongqing University (CN)
- Chongqing Three Gorges Central Hospital (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Breast Cancer Targets and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/bctt.s478110
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Science and Technology Commission
- Chongqing Medical University