Liver Injury in People With <scp>HIV</scp> on Antituberculosis and/or Antiretroviral Therapy—Assessing Causality Using the Updated Roussel Uclaf Causality Assessment Method
PWH with liver injury received multiple potentially implicated drugs, which may increase liver injury risk and complicate causality assessment. Compared with expert panel review, the RUCAM had low sensitivity in detecting probable or certain drug causes of liver injury.
Authors
- Hannah Gunter (ORCID: https://orcid.org/0000-0003-3027-0602)
- C Wendy Spearman (ORCID: https://orcid.org/0000-0003-3199-301X)
- Gary Maartens (ORCID: https://orcid.org/0000-0003-3080-6606)
- Ushma C. Mehta (ORCID: https://orcid.org/0000-0002-0032-3171)
- G. Tatz
- Karen Cohen (ORCID: https://orcid.org/0000-0002-1892-4207)
Institutions
- University of Cape Town (ZA)
- Groote Schuur Hospital (ZA)
Publication Details
- Journal
- Pharmacoepidemiology and Drug Safety
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/pds.5883
- Citations
- 3
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Academy of Medical Sciences