The association of dementia risk symptoms and functional activity in adults with Down syndrome
We explored the association of physical function and activities of daily living (ADLs) in aging adults with DS and their relationship with informant/caregiver report of dementia risk symptoms.Our findings demonstrated a significant relationship between a higher number of dementia risk symptoms observed and lower independence with ADLs, and impaired gait/balance, grip strength, and lower extremity strength.Further research with larger longitudinal studies is necessary to investigate any causative relationships among physical function, ADL function, and dementia risk symptoms.
Authors
- Lauren T. Ptomey (ORCID: https://orcid.org/0000-0002-1705-1643)
- Selena E. Washington (ORCID: https://orcid.org/0000-0002-1686-4802)
- Brian C. Helsel (ORCID: https://orcid.org/0000-0003-3362-3581)
- Susan Lynn Stark (ORCID: https://orcid.org/0000-0002-2816-7158)
- Rebecca M. Bollinger (ORCID: https://orcid.org/0000-0002-1931-8372)
- Amy E. Bodde (ORCID: https://orcid.org/0000-0002-8143-8105)
- Beau M. Ances (ORCID: https://orcid.org/0000-0003-3862-7397)
- Nora Smith
Institutions
- Washington University in St. Louis (US)
- University of Kansas Medical Center (US)
- Saint Louis University (US)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/trc2.70007
- Primary Topic
- Down syndrome and intellectual disability research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging