Modeling Overall Survival in Patients With Pancreatic Cancer From a Pooled Analysis of Phase <scp>II</scp> Trials

PFS/TTP is a more reliable surrogate than ORR and a strong predictor of OS in phase II trials of pancreatic cancer. Moreover, gamma GLM (log-link function) is a robust tool for modeling positively skewed survival data with non-constant variance, thus can be applied to other cancers' OS data of such nature.

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Publication Details

Journal
Cancer Medicine
Published
2024-10-01
DOI
https://doi.org/10.1002/cam4.70289
Citations
1
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.28
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article

Modeling Overall Survival in Patients With Pancreatic Cancer From a Pooled Analysis of Phase II Trials

Tanisha Tabassum Sayka Khan, Syeda Maliha Ahmed, Baejid Hossain Sagar, Eva Rahman Kabir et al.
1 citations
Cancer Medicine
Pancreatic and Hepatic Oncology Research
0.28
article

Modeling Overall Survival in Patients With Pancreatic Cancer From a Pooled Analysis of Phase II Trials

Tanisha Tabassum Sayka Khan, Syeda Maliha Ahmed, Baejid Hossain Sagar, Eva Rahman Kabir, Namara Mariam Chowdhury, Faruque Azam, Hasina Yasmin, Nasrin Ahmed Tahrim
article en
1 citations

Abstract

PFS/TTP is a more reliable surrogate than ORR and a strong predictor of OS in phase II trials of pancreatic cancer. Moreover, gamma GLM (log-link function) is a robust tool for modeling positively skewed survival data with non-constant variance, thus can be applied to other cancers' OS data of such nature.

Cancer MedicineVol. 13(19)
BRAC University (BD)
Good health and well-being
Openalex Percentile: Top 35%
Pancreatic and Hepatic Oncology Research
0.28
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